Reflux Oesophagitis: Clinical Guide for HCPs.

Master the diagnosis, risk assessment, and evidence-based management of Reflux Oesophagitis. Review current treatment protocols, including PPIs and surgical considerations, to prevent long-term complications like Barrett’s.

Reflux oesophagitis is a condition that affects millions worldwide, often silently damaging the lining of the oesophagus due to repeated exposure to stomach acid. Whether you're a healthcare professional, a student, or someone experiencing persistent heartburn, understanding this condition can be a game-changer for your health.

What is Reflux Oesophagitis?

Reflux oesophagitis is inflammation of the oesophagus caused by the backflow (reflux) of acidic stomach contents. This chronic irritation can damage the oesophageal lining, leading to discomfort, complications, and even precancerous changes if left untreated.

Causes of Reflux Oesophagitis:

• Gastroesophageal Reflux Disease (GERD) – the most common cause.

• Hiatal hernia – where part of the stomach moves into the chest cavity.

• Obesity – increases pressure on the stomach.

• Smoking and alcohol use – weaken the lower oesophageal sphincter (LES).

• Pregnancy – hormonal changes and abdominal pressure.

• Medications – such as NSAIDs, calcium channel blockers, or some antibiotics.

• Dietary triggers – spicy foods, citrus, caffeine, and chocolate.

Common Signs and Symptoms:

• Heartburn (burning sensation in the chest).

• Regurgitation of food or sour liquid.

• Difficulty swallowing (dysphagia).

• Sore throat or hoarseness.

• Chronic cough or wheezing.

• Chest discomfort, especially after meals or lying down.

Prevalence:

• Reflux oesophagitis affects approximately 15–30% of adults globally.

• More common in Western countries, but rising in Africa and Asia due to changing diets and lifestyle habits.

• Higher prevalence in individuals over 40 and those with obesity or sedentary lifestyles.

Prevention Tips:

• Maintain a healthy weight

• Avoid trigger foods and large meals

• Don’t lie down immediately after eating

• Quit smoking and limit alcohol intake

• Elevate the head of your bed if symptoms worsen at night

• Wear loose-fitting clothing around the abdomen

• Manage stress and anxiety, which can worsen reflux.

Treatment Options:

• Lifestyle modifications – diet changes, weight loss

Medications:

• Antacids – for quick relief

• H2 blockers – reduce acid production

• Proton pump inhibitors (PPIs) – most effective for healing

• Surgery (e.g., Nissen fundoplication) – in severe or resistant cases

• Regular follow-ups – especially if symptoms persist or worsen.

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